Treatment of Dermatofibrosarcoma Protuberans with Mohs Micrographic Surgery

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Mohs Micrographic Surgery for Dermatofibrosarcoma Protuberans of the Vulva

Introduction. Dermatofibrosarcoma Protuberans (DFSP) is a rare cutaneous tumour of low/intermediate malignant potential, which occasionally arises on the vulva. Historically, the treatment has been wide local excision (WLE). Mohs micrographic surgery (MMS) is now recommended to ensure precise margin control. MMS to treat DFSP of the trunk and extremities is well documented. However, no report t...

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Dermatofibrosarcoma protuberans of the vulva treated using mohs micrographic surgery.

dermatofibrosarcoma protuberans (DFSP) is a rare, low-grade sarcoma with a tendency for recurrence. The overall annual incidence is 4.2 per million, or 0.1% of all cancers. It tends to affect young to middle-aged adults and occurs more often in blacks than in whites, with no sex predilection. Dermatofibrosarcoma presents as a flesh-colored, violaceous, or reddish-brown nodule with persistent bu...

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Efficacy of Mohs micrographic surgery for the treatment of dermatofibrosarcoma protuberans: systematic review.

OBJECTIVE To summarize evidence about the recurrence of dermatofibrosarcoma protuberans (DFSP) following Mohs micrographic surgery (MMS). DATA SOURCES MEDLINE, Cochrane Library, EMBASE, Pascal, Biosis, CisMef, BDSP, Scopus, and Web of Knowledge databases were searched for the period January 1, 1995, to August 31, 2011. Search terms were Mohs micrographic surgery, dermatofibrosarcoma protuberans...

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Recurrent dermatofibrosarcoma protuberans treated with neoadjuvant imatinib mesylate followed by Mohs micrographic surgery

DFSP: Dermatofibrosarcoma protuberans INTRODUCTION Dermatofibrosarcoma protuberans (DFSP) is an uncommon, soft tissue sarcoma of mesenchymal origin characterized by its slow, infiltrative growth pattern and high risk of local recurrence after standard surgical excision. We describe a young man with a recurrent dermatofibrosarcoma protuberans after wide local excision treated with neoadjuvant im...

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Mohs micrographic surgery.

Mohs micrographic surgery (MMS) is a specialized type of minimal marginal surgery that offers cure rates superior to other options in the treatment of contiguous skin cancers in selected settings. Developed by Dr. Frederic E. Mohs, the technique originally required in situ tissue fixation before excision. Most Mohs micrographic surgeons now use the fresh tissue technique exclusively. Horizontal...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 1988

ISSN: 0003-4932

DOI: 10.1097/00000658-198801000-00019